Koizumi M, Sawada H, Goto M, Iijima A, Watari T, Kurosawa H, Kurumada H, Sugita K, Furukawa T
Department of Radiology, Cancer Institute Hospital, Tokyo.
Kaku Igaku. 1994 May;31(5):507-11.
123I-meta-iodobenzylguanidine (123I-MIBG) scintigraphy was performed in 9 patients who were suspected to have a neuroblastoma. Positive images were obtained in 4 patients who had a neuroblastoma. Negative images were obtained in 5 patients who did not have a neuroblastoma. 123I-MIBG scan revealed an active tumor in a patient who had received intensive chemotherapy for the recurrence of neuroblastoma with returning of all tumor markers including neuron specific enolase to normal range. This indicated that 123I-MIBG scan can be used to assess the effect of therapy.
对9例疑似神经母细胞瘤的患者进行了123I-间碘苄胍（123I-MIBG）闪烁扫描。4例患有神经母细胞瘤的患者获得了阳性图像。5例未患神经母细胞瘤的患者获得了阴性图像。123I-MIBG扫描显示，一名因神经母细胞瘤复发接受强化化疗且所有肿瘤标志物（包括神经元特异性烯醇化酶）恢复至正常范围的患者存在活动性肿瘤。这表明123I-MIBG扫描可用于评估治疗效果。
