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[绝经与年龄对克罗地亚北部城市环境中女性骨密度的影响]

[The effect of menopause and age on bone mineral density in women living in an urban environment in northern Croatia].

作者信息

Barilar-Antoljak N, Korsić M, Dekanić D, Jelcić J, Kusec V, Cvijetić S, Kozić-Rukavina B, Antoljak T, Topić E, Aganović I

机构信息

Znanstvena jedinica Rebro, Klinicki bolnicki centar, Zagreb.

出版信息

Lijec Vjesn. 1994 Jan-Feb;116(1-2):10-4.

PMID:8028430
Abstract

The results of measurement of bone mass in three areas (lumbar spine, femoral neck and radius) where osteoporotic fractures most commonly occur are presented. The sample of 103 women was divided into three groups: premenopausal, early menopausal (up to 5 years of menopause) and late menopausal (more than 5 years of menopause). Both menopausal groups were additionally divided in two subgroups regarding the previous fractures. A statistically significant difference (p < 0.01) was found between bone mineral density (lumbar spine, femoral neck) and bone mineral content (radius) among all the groups. No difference was established for bone mass between postmenopausal women with and without fractures (> 0.05) by using the Kruskal-Wallis analysis of variance. A significant negative correlation (p < 0.01) was found between bone mass in all three tested regions on one side vs age of women as well as the period of menopause on the other. These results indicate that bone mass is significantly decreased in postmenopausal women. Therefore, the authors recommend densitometry to be employed in all postmenopausal women.

摘要

本文给出了骨质疏松性骨折最常发生的三个部位(腰椎、股骨颈和桡骨)的骨量测量结果。103名女性样本被分为三组:绝经前、绝经早期(绝经后5年内)和绝经晚期(绝经后5年以上)。两个绝经组又根据既往骨折情况进一步分为两个亚组。所有组之间的骨密度(腰椎、股骨颈)和骨矿物质含量(桡骨)存在统计学显著差异(p < 0.01)。通过Kruskal-Wallis方差分析,绝经后有骨折和无骨折女性之间的骨量无差异(> 0.05)。一侧所有三个测试区域的骨量与女性年龄以及绝经时间之间存在显著负相关(p < 0.01)。这些结果表明绝经后女性骨量显著降低。因此,作者建议对所有绝经后女性采用骨密度测量法。

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