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[奥斯陆66岁女性的骨矿物质密度与骨折发生率]

[Bone mineral density and occurrence of fractures in 66-year old women in Oslo].

作者信息

Halse J, Nordal K P, Knudtzon J, Stokke O, Glattre E

机构信息

Medisinsk avdeling B, Rikshospitalet, Oslo.

出版信息

Tidsskr Nor Laegeforen. 1993 Jun 10;113(15):1846-8.

PMID:8322323
Abstract

During 1991 we examined 196 randomly chosen females born in 1925 and resident in Oslo. 40% had suffered fractures of the appendicular skeleton, most commonly of the forearm and the ankles, after the menopause. Results from bone mineral density measurements of the lumbar spine (L2-4) and the femoral neck were not significantly lower, while results from the distal 1/3 of the forearm site were significantly lower, among participants with fractures than among participants without fractures. The values for bone mineral density obtained from these three sites corresponded with the values reported from other countries. Biochemical indices of calcium metabolism were similar in fracture and non-fracture subjects. Age at menopause, weight, height and demographic characteristics were also similar in the two groups. We conclude that low bone mineral density cannot be the sole explanation of the very high prevalence of fractures among female residents of Oslo found in the present and previous studies.

摘要

1991年,我们对1925年出生且居住在奥斯陆的196名随机挑选的女性进行了检查。40%的女性在绝经后发生过附属骨骼骨折,最常见的是前臂和脚踝骨折。腰椎(L2 - 4)和股骨颈骨密度测量结果在骨折参与者和未骨折参与者之间没有显著差异,而在前臂远端1/3部位,骨折参与者的测量结果显著低于未骨折参与者。从这三个部位获得的骨密度值与其他国家报告的值相符。骨折和未骨折受试者的钙代谢生化指标相似。两组的绝经年龄、体重、身高和人口统计学特征也相似。我们得出结论,骨密度低不能唯一解释在本研究及之前研究中发现的奥斯陆女性居民骨折患病率极高的现象。

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