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吡喹酮类似物治疗肠道绦虫和吸虫感染的临床试验结果分析。2. 肝吸虫感染（华支睾吸虫病、肝片吸虫病）和血吸虫病的治疗

[An analysis of the results of clinical trials of praziquantel analogs in intestinal cestode and trematode infections. 2. The treatment of liver trematode infections (opisthorchiasis, fascioliasis) and schistosomiasis].

作者信息

Bronshteĭn A M, Mel'nikova L I, Firsova R A, Legon'kov Iu A

出版信息

Med Parazitol (Mosk). 1993 Mar-Apr(2):16-7.

PMID:8028557
Abstract

The authors did not detect any differences in the efficacies and tolerance of praziquantel analogs manufactured by various firms (azinox, Russia; pikitor, China; cesol, cisticide, biltricide, Bayer, Merk, Germany, India). These drugs were found highly effective in opisthorchiasis (87.8%) and schistosomiasis (91.7%) and ineffective in fascioliasis. The efficacy and tolerance of azinox, a drug manufactured in this country, was similar to those of its foreign analogs.

摘要

作者未发现不同公司生产的吡喹酮类似物（俄罗斯的azinox；中国的pikitor；德国、印度的拜耳公司生产的cesol、cisticide、biltricide、Merk公司生产的吡喹酮）在疗效和耐受性方面存在差异。这些药物在华支睾吸虫病（87.8%）和血吸虫病（91.7%）中显示出高效，而在肝片吸虫病中无效。该国生产的药物azinox的疗效和耐受性与其国外类似物相似。

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