Paluch D, Staniszewska-Kuś J, Solski L, Szymonowicz M, Usakiewicz B
Zakład Chirurgii Eksperymentalnej i Badania Biomateriałów, Wrocławiu.
Polim Med. 1993;23(3-4):3-13.
In the Department of Experimental Surgery and Biomaterials Research in Wrocłow Medical Academy standard and qualifying evaluation of 5 kinds of hydrogel dressings POLGEL produced in the Institute of Physico-Chemistry and Technology of Polymers of produced in Silesian Polytechnique has been carried out. Dressings Polgel were obtained as a result of copolymerization of acrylamide and methylene-bis-acrylamide in aqueous solution. On the basis of introductory experiments for qualifying evaluation dressing Polgel M modified with glycerin in the form of foil and dressing Polgel T--in the form of jelly were chosen. Both kinds of dressings did not cause haemolytic, toxic or irritative effects. In pathomorphological experiments moderate tissues reaction was noticed what signifies good biological characteristics of the evaluated dressings. The process of healing of injuries treated with dressings Polgel M proceeded well and epidermis creating was quicker in comparison with injuries treated with traditional dressing. On the basis of the carried out experiments it was noticed that dressings Polgel M and T satisfy the requirements made for the type of materials.
在弗罗茨瓦夫医科大学实验外科与生物材料研究部，对西里西亚理工大学聚合物物理化学与技术研究所生产的5种水凝胶敷料POLGEL进行了标准和合格评估。敷料Polgel是通过丙烯酰胺和亚甲基双丙烯酰胺在水溶液中共聚得到的。在资格评估的初步实验基础上，选择了以箔片形式用甘油改性的敷料Polgel M和以果冻形式的敷料Polgel T。这两种敷料均未引起溶血、毒性或刺激作用。在病理形态学实验中，观察到中等程度的组织反应，这表明所评估敷料具有良好的生物学特性。与用传统敷料治疗的伤口相比，用敷料Polgel M治疗的伤口愈合过程进展良好，表皮形成更快。根据所进行的实验，发现敷料Polgel M和T符合对材料类型提出的要求。
