Eikmeier G, Lodemann E
Department of Psychiatry, ZKH Reinkenheide, Bremerhaven, Germany.
Pharmacopsychiatry. 1994 Mar;27(2):63-4. doi: 10.1055/s-2007-1014278.
PINV was recorded during a warned reaction time paradigm in 16 chronic schizophrenics in remission. Clinical symptoms were assessed by BPRS, SANS, and the anhedonia scale of the Chapman Questionnaire. Ten healthy controls were studied in the same manner. Over the frontocentral area we found a significantly elevated PINV amplitude with an altered topographical distribution in the patient group. The difference values "PINVCz-PINVFz" were correlated negatively with primary negative symptoms of schizophrenia.
在16名处于缓解期的慢性精神分裂症患者中，在一个预先警告的反应时间范式下记录了诱发性负变（PINV）。通过简明精神病评定量表（BPRS）、阴性症状评定量表（SANS）和查普曼问卷的快感缺失量表评估临床症状。以同样的方式研究了10名健康对照者。在额中央区，我们发现患者组的PINV波幅显著升高，其地形分布改变。“PINV中央区 - PINV额区”的差值与精神分裂症的原发性阴性症状呈负相关。
