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Altered fronto-central PINV topography and the primary negative syndrome in schizophrenia.

作者信息

Eikmeier G, Lodemann E, Olbrich H M, Pach J, Zerbin D, Gastpar M

机构信息

Department of General Psychiatry, University of Essen, Germany.

出版信息

Schizophr Res. 1993 Jan;8(3):251-6. doi: 10.1016/0920-9964(93)90023-c.

DOI:10.1016/0920-9964(93)90023-c
PMID:8435386
Abstract

Postimperative negative variation (PINV) was recorded during a warned reaction time paradigm in 16 chronic DSM-IIIR schizophrenics in remission. Clinical symptoms were assessed by BPRS, SANS and the anhedonia scale of the Chapman Questionnaire. Ten healthy controls were studied in the same manner. Over the fronto-central area we found a significantly elevated PINV amplitude with an altered topographical distribution in the patient group. The difference values 'PINV Cz-PINV Fz' were correlated negatively with primary negative symptoms of schizophrenia.

摘要

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