Brkljacić B, Mrzljak V, Drinković I, Soldo D, Sabljar-Matovinović M, Hebrang A
Department of Radiology, University Hospital Merkur, Medical School, University of Zagreb, Croatia.
Radiology. 1994 Aug;192(2):549-54. doi: 10.1148/radiology.192.2.8029430.
To evaluate duplex Doppler sonography to assess renal vascular resistance (RVR) in diabetic patients.
Resistive indexes (RIs) and pulsatility indexes (PIs) were measured in intrarenal arteries of 144 patients with diabetes mellitus and 61 control subjects. RIs and PIs were compared for control subjects and patients with diabetic nephropathy and correlated with laboratory and clinical findings.
In control subjects, the mean RI was 0.595 +/- 0.033 (standard deviation) and mean PI was 1.001 +/- 0.105. Elevated RIs and PIs accompanied progression of nephropathy. Statistically significant (P < .001) correlations were observed between both RI and PI and serum creatinine level, creatinine clearance rate, systolic and diastolic blood pressure measurements, and patient age.
Doppler indexes reflect increased RVR in diabetic nephropathy and correlate with laboratory and clinical parameters, but RI and PI measurements offer no advantages over these parameters to predict disease progress or in patient care.
评估双功多普勒超声检查以评估糖尿病患者的肾血管阻力（RVR）。
测量了144例糖尿病患者和61例对照者肾内动脉的阻力指数（RI）和搏动指数（PI）。比较了对照者与糖尿病肾病患者的RI和PI，并将其与实验室及临床检查结果进行关联分析。
对照者的平均RI为0.595±0.033（标准差），平均PI为1.001±0.105。随着肾病进展，RI和PI升高。RI和PI与血清肌酐水平、肌酐清除率、收缩压和舒张压测量值以及患者年龄之间均存在统计学显著相关性（P <.001）。
多普勒指数反映了糖尿病肾病中RVR的增加，并与实验室及临床参数相关，但RI和PI测量在预测疾病进展或患者护理方面并不优于这些参数。
