Volz A, Renard N, Alame T, Efira A
Départment de Médecine Interne, Hôpital St. Pierre, Bruxelles.
Rev Med Brux. 1994 Mar-Apr;15(2):76-9.
A 58-year-old male presented with a three years history of atopic asthma, fluctuating eosinophilia and, at the moment of diagnosis, systemic vasculitis of brutal onset affecting skin and peripheral nerves. Demonstration of eosinophilic infiltrates and granulomata in involved tissues confirmed the clinical diagnosis of Churg-Strauss syndrome. Therapy with high-dose methylprednisolone and cyclophosphamide was followed by normalization of blood cell count and partial recovery of clinical manifestations, with persisting damage to the peripheral nerves.
一名58岁男性,有三年特应性哮喘病史,嗜酸性粒细胞增多症波动,诊断时出现急性起病的累及皮肤和周围神经的系统性血管炎。受累组织中嗜酸性粒细胞浸润和肉芽肿的证实了变应性肉芽肿性血管炎(Churg-Strauss综合征)的临床诊断。大剂量甲泼尼龙和环磷酰胺治疗后,血细胞计数恢复正常,临床表现部分恢复,但周围神经仍有持续性损伤。