Hammar L, Hirsch I, Machado A, De Mareuil J, Baillon J, Chermann J C
Department of Veterinary Virology, Biomedical Center, Uppsala, Sweden.
Ann N Y Acad Sci. 1994 Jun 6;724:166-9. doi: 10.1111/j.1749-6632.1994.tb38907.x.
Lectins with specificity for terminal mannose residues and anti-mannan antibodies are assumed to neutralize HIV-1 by binding to the viral glycoproteins. In this report we demonstrate that one such agents, the lectin from Galanthus nivalis (GNA), blocks infection also at the target cell level.