Torrado S, Torrado S, Cadórniga R
Department of Pharmaceutical Technology, Faculty of Pharmacy, Complutense University, Madrid, Spain.
J Pharm Biomed Anal. 1994 Mar;12(3):383-7. doi: 10.1016/0731-7085(94)90015-9.
Second-derivative spectroscopy, colorimetry and fluorescence spectroscopy have been compared with a high-performance liquid chromatographic (HPLC) method for the assay of salicylic acid in preparations of aspirin. Results are presented for the linearity, sensitivity and reproducibility of these methods. The second-derivative spectroscopic and the HPLC methods were acceptable in terms of linearity, sensitivity and inter-day reproducibility and were convenient for the routine analysis of salicylic acid in aspirin preparations.
已将二阶导数光谱法、比色法和荧光光谱法与高效液相色谱（HPLC）法进行比较，以测定阿司匹林制剂中的水杨酸含量。给出了这些方法的线性、灵敏度和重现性结果。二阶导数光谱法和HPLC法在线性、灵敏度和日间重现性方面是可接受的，并且便于对阿司匹林制剂中的水杨酸进行常规分析。
