Christian T F, Gibbons R J
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Cardiol Clin. 1994 May;12(2):247-60.
The role of radionuclide perfusion imaging during acute coronary syndromes are discussed. The development of Tc-99m sestamibi has provided for significant advances in this field. This radionuclide enables a measurement of myocardium at risk and final infarct size and, consequently, myocardial salvage during reperfusion therapy. Analysis of acute images during infarction also allows for a measure of collateral flow to the infarct zone. This agent also can be used to triage patients with spontaneous chest pain suggestive of unstable angina.
本文讨论了放射性核素灌注成像在急性冠状动脉综合征中的作用。锝-99m 甲氧基异丁基异腈（Tc-99m sestamibi）的发展为此领域带来了重大进展。这种放射性核素能够测量危险心肌和最终梗死面积，从而评估再灌注治疗期间的心肌挽救情况。梗死期间急性图像的分析还可测量梗死区的侧支血流。这种药物还可用于对提示不稳定型心绞痛的自发性胸痛患者进行分流。
