Nishida Y, Watanabe S, Matsuo H, Kotoo Y, Oda H, Matsubara T, Sugiyama A, Matsuno Y, Kano M, Tanihata S
Division of Cardiology and Radiology, Prefectural Gifu Hospital.
Kaku Igaku. 1993 Jan;30(1):79-83.
The determination of the myocardium at risk before intervention and the change in that region after intervention constitute a promising measurement tool for the assessment of acute therapy. We used 99mTc PPN-1011 in 4 patients with acute myocardial ischemia (2 patients with acute myocardial infarction, 2 unstable angina) and subsequent successful reperfusion. All 4 patients had perfusion defect on the pre-reperfusion image. Perfusion abnormality on post-reperfusion image was all improved significantly compared with pre-reperfusion image, suggesting the efficacy of acute treatment in acute myocardial ischemia. We conclude that 99mTc PPN-1011 scintigraphy is useful method for the assessment of myocardial area at risk and the efficacy of PTCA/PTCR in myocardial infarction and unstable angina.
干预前对心肌危险区域的确定以及干预后该区域的变化，构成了一种很有前景的用于评估急性治疗效果的测量工具。我们对4例急性心肌缺血患者（2例急性心肌梗死，2例不稳定型心绞痛）使用了99mTc PPN - 1011，随后成功实现再灌注。所有4例患者在再灌注前图像上均有灌注缺损。与再灌注前图像相比，再灌注后图像上的灌注异常均有显著改善，提示急性治疗对急性心肌缺血有效。我们得出结论，99mTc PPN - 1011闪烁扫描术是评估心肌梗死和不稳定型心绞痛中危险心肌区域及PTCA/PTCR疗效的有用方法。
