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两种氯化联苯异构体:4-氯联苯和十氯联苯在泌乳奶牛体内的分布与排泄

Distribution and excretion of two chlorinated biphenyl isomers: 4-chlorobiphenyl and decachlorobiphenyl in lactating bovine.

作者信息

Platonow N S, Meads E B

出版信息

Can J Comp Med. 1975 Jan;39(1):104-6.

Abstract

One lactating cow was given a 4-chlorobiphenyl (50 mgm/kgm) as a single oral dose and was killed seven days postadministration. The presence of this compound was not detected in tissues, urine and milk. However, 28.9% of the total dose given was recovered in feces during the period of seven days postadministration. Another lactating cow received decachlorobiphenyl orally as single dose (50 mgm/kgm) and was also killed seven days postadministration. This totally chlorinated biphenyl was recovered at low concentrations from all tissues analyzed. The cumulative excretion into milk and feces accounted for 0.025 and 25.02% respectively. Decachlorobiphenyl was detected in urine.

摘要

给一头泌乳奶牛单次口服4-氯联苯(50毫克/千克),给药后7天处死。在组织、尿液和牛奶中未检测到该化合物。然而,给药后7天内,粪便中回收了给药总量的28.9%。另一头泌乳奶牛单次口服十氯联苯(50毫克/千克),给药后7天也被处死。从所有分析的组织中均以低浓度回收了这种全氯联苯。进入牛奶和粪便的累积排泄量分别占0.025%和25.02%。尿液中检测到了十氯联苯。

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Metabolism of chlorobiphenyls in the goat and cow.山羊和奶牛体内氯联苯的代谢
J Agric Food Chem. 1975 Mar-Apr;23(2):259-61. doi: 10.1021/jf60198a053.

本文引用的文献

2
Accumulation of polychlorinated biphenyls in ecosystems.多氯联苯在生态系统中的积累。
Environ Health Perspect. 1972 Apr;1:39-45. doi: 10.1289/ehp.720139.
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Chromatographic and biological aspects of polychlorinated biphenyls.多氯联苯的色谱及生物学特性
J Chromatogr. 1972 Jun 7;68(2):345-426. doi: 10.1016/s0021-9673(00)85724-6.

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