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多氯联苯(Aroclor 1254)在公鸡长期饲养试验中的分布及某些影响

The distribution and some effects of polychlorinated biphenyls (Aroclor 1254) in cockerels during prolonged feeding trial.

作者信息

Platanow N S, Funnell H S

出版信息

Can J Comp Med. 1972 Apr;36(2):89-93.

Abstract

A ration containing 500 ppm of polychlorinated biphenyls (PCB) was fed to one month old cockerels for periods up to 12 weeks. The distribution of PCB was determined in the brain, liver, kidneys and blood as well as in the muscular and adipose tissues. Tissue concentrations of PCB increased linearly with time. Small changes were detected on the chromatograms of the liver, fat and blood extracts.A significant decrease in the size of the combs and testicles in PCB-treated birds was noted. This decrease appeared as early as one week after the start of PCB administration.

摘要

将含有500 ppm多氯联苯(PCB)的日粮喂给1月龄的小公鸡,持续12周。测定了PCB在脑、肝、肾、血液以及肌肉和脂肪组织中的分布情况。组织中PCB的浓度随时间呈线性增加。在肝脏、脂肪和血液提取物的色谱图上检测到了微小变化。注意到经PCB处理的鸡的鸡冠和睾丸尺寸显著减小。这种减小在开始给予PCB后1周就出现了。

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本文引用的文献

1
Chlorinated hydrocarbons in British wildlife.英国野生动物体内的氯代烃
Nature. 1967 Oct 21;216(5112):227-9. doi: 10.1038/216227a0.
2
The redistribution of stored DDT in cockerels under the influence of food deprivation.
Toxicol Appl Pharmacol. 1969 Sep;15(2):420-32. doi: 10.1016/0041-008x(69)90040-4.
3
Polychlorinated biphenyls in the global ecosystem.全球生态系统中的多氯联苯。
Nature. 1968 Dec 14;220(5172):1098-102. doi: 10.1038/2201098a0.

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