Platonow N S, Karstad L H
Can J Comp Med. 1973 Oct;37(4):391-400.
Poisoning occurred in 32 mink fed diets containing meat from cows which had been fed a polychlorinated biphenyl (PCB), Aroclor 1254. No live kits were produced and all adult mink died during a 105 day period of feeding a ration containing 3.57 ppm of PCB. At a level of 0.64 ppm of PCB in ration one of 12 mink produced three kits, all of which died during the first day after birth. Clinical signs were limited to weight loss and passage of black tarry feces. The gross lesions seen were yellowish discoloration of the liver and hemorrhage into the abdominal cavity or gastrointestinal tract. Microscopic lesions were nephrosis, fatty de-generation and necrosis of the liver, brain edema, disseminated intravascular coagulation, and fibrosis of coronary arteries. It is concluded that mink are highly sensitive to small quantities of PCB fed for an extended period of time.
32只水貂食用了含有来自喂食过多氯联苯（PCB）——氯丹1254的奶牛的肉的日粮后发生中毒。在喂食含3.57 ppm多氯联苯的日粮的105天期间，没有幼崽存活，所有成年水貂死亡。当日粮中多氯联苯含量为0.64 ppm时，12只水貂中有1只产下3只幼崽，所有幼崽均在出生后第一天死亡。临床症状仅限于体重减轻和排出黑色焦油状粪便。肉眼可见的病变为肝脏发黄以及腹腔或胃肠道出血。显微镜下病变为肾病、肝脏脂肪变性和坏死、脑水肿、弥散性血管内凝血以及冠状动脉纤维化。结论是水貂对长时间喂食的少量多氯联苯高度敏感。
