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一种鸟类着丝粒重复DNA组分的序列保守性

Sequence conservation of an avian centromeric repeated DNA component.

作者信息

Madsen C S, Brooks J E, de Kloet E, de Kloet S R

机构信息

Department of Immunology and Medical Microbiology, University of Florida, Gainesville 32610.

出版信息

Genome. 1994 Jun;37(3):351-5. doi: 10.1139/g94-050.

Abstract

The approximately 190-bp centromeric repeat monomers of the spur-winged lapwing (Vanellus spinosus, Charadriidae), the Chilean flamingo (Phoenicopterus chilensis, Phoenicopteridae), the sarus crane (Grus antigone, Gruidae), parrots (Psittacidae), waterfowl (Anatidae), and the merlin (Falco columbarius, Falconidae) contain elements that are interspecifically highly variable, as well as elements (trinucleotides and higher order oligonucleotides) that are highly conserved in sequence and relative location within the repeat. Such conservation suggests that the centromeric repeats of these avian species have evolved from a common ancestral sequence that may date from very early stages of avian radiation.

摘要

黑翅麦鸡(Vanellus spinosus,麦鸡科)、智利火烈鸟(Phoenicopterus chilensis,红鹳科)、赤颈鹤(Grus antigone,鹤科)、鹦鹉(鹦鹉科)、水禽(鸭科)和矛隼(Falco columbarius,隼科)的约190个碱基对的着丝粒重复单体包含种间高度可变的元件,以及在重复序列中的序列和相对位置上高度保守的元件(三核苷酸和高阶寡核苷酸)。这种保守性表明,这些鸟类物种的着丝粒重复序列是从一个共同的祖先序列进化而来的,这个祖先序列可能可以追溯到鸟类辐射的早期阶段。

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