Panda S, Sarkar S, Mandal B K, Singh T B, Singh K L, Mitra D K, Sarkar K, Tripathy S P, Deb B C
ICMR Unit for Research on AIDS in north eastern states of India, Calcutta.
J Infect. 1994 Mar;28(2):167-73. doi: 10.1016/s0163-4453(94)95620-0.
Since 1989, injecting drug use (IDU) related HIV infection has affected thousands of young adults in Manipur, a north eastern state of India bordering Myanmar following a similar kind of epidemic in adjoining countries like Thailand and Myanmar. During a clinical surveillance of a group of HIV positive IDUs for a natural history study at Manipur, herpes zoster (HZ) emerged as the most specific early HIV related illness (positive predictive value of 100%) in patients belonging to the age group of 12-45 years. Data collected from the dermatology departments of the two main hospitals of the state revealed that there had been an epidemic of HZ since 1990 (rate of 1990 being 11.3/1000 compared to 6.5/1000 in 1989, P value < 0.0001) among males of 12-45 years. The epidemic of HZ has been attributed to the preceding epidemic of IDU related HIV in the same age and gender group occurring 1 year earlier. HZ should be recognised as a marker condition similar to tuberculosis indicating the necessity of screening for HIV in regions where the dual problem of IDU and HIV exist in young adults.
自1989年以来，在印度东北部与缅甸接壤的曼尼普尔邦，注射吸毒（IDU）相关的艾滋病毒感染影响了数千名年轻人，此前在泰国和缅甸等邻国也出现了类似的疫情。在曼尼普尔邦对一组艾滋病毒阳性注射吸毒者进行自然史研究的临床监测期间，带状疱疹（HZ）在12至45岁年龄组的患者中成为最具特异性的早期艾滋病毒相关疾病（阳性预测值为100%）。从该邦两家主要医院的皮肤科收集的数据显示，自1990年以来，12至45岁男性中出现了带状疱疹疫情（1990年的发病率为11.3/1000，而1989年为6.5/1000，P值<0.0001）。带状疱疹疫情被归因于同一年龄和性别组中提前一年出现的注射吸毒相关艾滋病毒疫情。在存在年轻成年人注射吸毒和艾滋病毒双重问题的地区，带状疱疹应被视为与结核病类似的标志性疾病，这表明有必要对艾滋病毒进行筛查。
