Chan E L, Swaminathan R
Department of Chemical Pathology, Chinese University of Hong Kong, Prince of Wales Hospital.
J Lab Clin Med. 1994 Jul;124(1):37-41.
The effect of feeding high protein (40%) and high salt intake (18 gm/L of sodium chloride in drinking water) for 4 months on the urinary excretion of calcium and hydroxyproline (OHP) in sham operated and oophorectomized (OX) rats was studied. OX rats had higher body weight and increased excretion of calcium and OHP. Feeding a high-salt diet caused an increase in the excretion of calcium, phosphate, and OHP. The high-protein diet had a similar effect. There was a significant interaction between the effects of salt and protein on calcium excretion. OX did not influence the effect of high salt or high protein intakes. It is concluded that high protein and/or high salt intake increases the excretion of calcium and OHP. The effect is seen even after 4 months of the diet. Oophorectomy did not cause any additional effect.
研究了对假手术大鼠和去卵巢（OX）大鼠进行4个月的高蛋白（40%）和高盐摄入（饮用水中氯化钠含量为18克/升）喂养，对钙和羟脯氨酸（OHP）尿排泄的影响。OX大鼠体重更高，钙和OHP的排泄增加。高盐饮食导致钙、磷和OHP排泄增加。高蛋白饮食有类似效果。盐和蛋白质对钙排泄的影响之间存在显著交互作用。OX不影响高盐或高蛋白摄入的效果。得出的结论是，高蛋白和/或高盐摄入会增加钙和OHP的排泄。即使在饮食4个月后仍可见此效果。去卵巢未产生任何额外影响。
