Torabinejad M, Higa R K, McKendry D J, Pitt Ford T R
Department of Endodontics School of Dentistry, Loma Linda University, CA.
J Endod. 1994 Apr;20(4):159-63. doi: 10.1016/S0099-2399(06)80326-2.
The purpose of this study was to compare the amount of dye leakage (in the presence versus absence of blood) in root end cavities filled with amalgam, Super EBA, IRM, and a mineral trioxide aggregate. After removing the anatomical crowns of 90 extracted human teeth, their roots were instrumented and obturated. Except for their apical 2 mm, the root surfaces were sealed with nail polish. After removal of the apical 2 to 3 mm of each root, a standardized root end cavity was prepared. Five root ends were filled with gutta-percha and no sealer, and another five root ends were filled with sticky wax. These served as positive and negative controls, respectively. The remaining 80 roots were divided into four equal groups and filled with the test materials. For each material, half of the root end cavities were dried prior to placing the filling material. The remaining half were filled after they were contaminated with blood. All 90 roots were then immediately placed in 1% methylene blue dye for 72 h. Finally, the roots were split and linear dye penetration was measured and statistically analyzed (analysis of variance). Presence or absence of blood had no significant effect on the amount of dye leakage. However, the results showed that there was a significant leakage difference between the root end filling materials (p < 0.0001). Mineral trioxide aggregate leaked significantly less than other materials tested with or without blood contamination of the root end cavities.
本研究的目的是比较用汞合金、Super EBA、IRM和一种三氧化矿物凝聚体充填的根尖倒充填窝洞中的染料渗漏量（有血与无血情况下）。在去除90颗拔除的人牙的解剖冠后，对其牙根进行预备和充填。除根尖2mm外，牙根表面用指甲油密封。在去除每颗牙根根尖2至3mm后，制备标准化的根尖倒充填窝洞。五个根尖倒充填窝洞用牙胶充填且不使用封闭剂，另外五个根尖倒充填窝洞用粘性蜡充填。这些分别作为阳性和阴性对照。其余80颗牙根分为四组，每组数量相等，并用试验材料充填。对于每种材料，一半根尖倒充填窝洞在放置充填材料前进行干燥。另一半在被血液污染后进行充填。然后将所有90颗牙根立即置于1%亚甲蓝染料中72小时。最后，将牙根劈开，测量线性染料渗透并进行统计学分析（方差分析）。有无血液对染料渗漏量无显著影响。然而，结果显示根尖倒充填材料之间存在显著的渗漏差异（p<0.0001）。无论根尖倒充填窝洞有无血液污染，三氧化矿物凝聚体的渗漏均显著少于其他受试材料。
