Cover H, Irwin M
Department of Psychiatry, University of California, San Diego.
J Behav Med. 1994 Apr;17(2):217-23. doi: 10.1007/BF01858106.
Depressed patients show a reduction of natural killer (NK) cell activity which may be associated with specific depressive symptoms. The present study demonstrated that sleep disturbance and retardation, but not other depressive symptoms, were negatively correlated with NK activity in 38 depressed patients. Specific behavioral changes in depression such as sleep disturbance and retardation were found to predict 16% of the variance of cytotoxicity levels in depression.
抑郁症患者的自然杀伤（NK）细胞活性降低，这可能与特定的抑郁症状有关。本研究表明，在38名抑郁症患者中，睡眠障碍和迟缓与NK活性呈负相关，而非其他抑郁症状。抑郁症中如睡眠障碍和迟缓等特定行为变化被发现可预测抑郁症中细胞毒性水平变异的16%。
