Azizi B H, Henry R L
Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur.
Respir Med. 1994 May;88(5):349-56. doi: 10.1016/0954-6111(94)90040-x.
Spirometric recordings of 1098 Malaysian children who were free of respiratory symptoms were examined by least square regression analysis of log-transformed lung function data. Ethnic differences were observed in FVC, FEV1, and FEF25-75 independent of father's education, exposure to passive smoking, wood stove, kerosene stove and mosquito repellents, family history of chest illness and history of allergy, after adjusting for standing height, age and sex. Exposure to kerosene stove was significantly associated with reduced FVC and FEV1 indicating that environmental factors may impair lung function in symptomless children. Prediction equations were derived for each ethnic group and sex. Comparison with data from the literature showed that Malaysian children had lower lung function values than Caucasian children. Generally, Chinese children had higher FEV1, FVC and FEF25-75 than Malay and Indian children. Indian children consistently had the lowest lung function values. Since these ethnic differences were independent of environmental and other host factors, anthropometric variations could be an explanation.
通过对经对数转换的肺功能数据进行最小二乘回归分析，对1098名无呼吸道症状的马来西亚儿童的肺量计记录进行了检查。在调整了身高、年龄和性别后，观察到在FVC、FEV1和FEF25 - 75方面存在种族差异，且这些差异与父亲的教育程度、被动吸烟暴露、使用木炉、煤油炉和驱蚊剂、胸部疾病家族史以及过敏史无关。接触煤油炉与FVC和FEV1降低显著相关，这表明环境因素可能会损害无症状儿童的肺功能。为每个种族和性别推导了预测方程。与文献数据比较显示，马来西亚儿童的肺功能值低于白种儿童。一般来说，华裔儿童的FEV1、FVC和FEF25 - 75高于马来族和印度族儿童。印度族儿童的肺功能值一直最低。由于这些种族差异与环境和其他宿主因素无关，人体测量学差异可能是一个解释。
