Andrews J R, Ainsworth R, Abernethy D
School of Biological Sciences, Victoria University of Wellington, New Zealand.
Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):200-3. doi: 10.1016/0035-9203(94)90295-x.
The first known human case of Trichinella pseudospiralis myositis is described. A 33 years old woman reported 5 years of relatively mild symptoms of tiredness, muscle fatigue and muscle pain after exercise. She had minimal proximal weakness. Creatinine kinase was significantly elevated, and muscle biopsy showed polymyositis and Trichinella larvae. Steroid treatment dramatically worsened the weakness. Treatment with albendazole led to complete resolution of symptoms and laboratory abnormalities. Diagnosis and identification of the parasite were based on the distinctive appearance of the unencapsulated larvae and their movement in fresh muscle, plus clinical and laboratory findings.
本文描述了首例已知的人感染伪旋毛虫性肌炎病例。一名33岁女性报告称，在运动后出现5年相对较轻的疲劳、肌肉乏力和肌肉疼痛症状。她近端肌无力症状轻微。肌酸激酶显著升高，肌肉活检显示为多发性肌炎且发现了旋毛虫幼虫。类固醇治疗使肌无力症状显著恶化。使用阿苯达唑治疗后症状和实验室异常表现完全消失。寄生虫的诊断和鉴定基于未包囊幼虫的独特外观及其在新鲜肌肉中的活动，以及临床和实验室检查结果。
