Bryceson A D, Murphy A, Moody A H
Hospital for Tropical Diseases, London, UK.
Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):226-8. doi: 10.1016/0035-9203(94)90308-5.
Five preparations of ointment containing aminosidine were used to treat lesions of 'Old World' cutaneous leishmaniasis. A preparation containing 12-15% aminosidine with 10% urea in white soft paraffin was nontoxic. 23 of 27 patients treated healed in a mean of 6.7 weeks, the ointment being applied daily for up to 12 weeks.
使用了五种含氨基糖苷的软膏制剂来治疗“旧世界”皮肤利什曼病的病灶。一种在白色软石蜡中含有12 - 15%氨基糖苷和10%尿素的制剂无毒。27例接受治疗的患者中有23例平均在6.7周内痊愈,该软膏每天使用,最长使用12周。