Mastroeni I, Vescia N, Pompa M G, Cattaruzza M S, Marini G P, Fara G M
Department of Experimental Biology, University of Cagliari, Italy.
Vaccine. 1994 May;12(6):518-20. doi: 10.1016/0264-410x(94)90310-7.
A serological study has been performed to detect the antibody response to full schedules of two anti-rabies vaccines (PDEV and HDCV). Subjects aged > 50 years, compared with subjects 11-25 years, showed significantly lower titres after the 4th dose (and, to a lesser extent, after the 5th dose), suggesting that, among the elderly, the 6th dose is strongly desirable.
已经进行了一项血清学研究，以检测对两种狂犬病疫苗（PDEV和HDCV）完整接种程序的抗体反应。与11至25岁的受试者相比，50岁以上的受试者在第4剂后（以及在较小程度上在第5剂后）的滴度显著较低，这表明在老年人中，强烈建议接种第6剂。
