Scheinin S A, Cooley D A
Division of Cardiovascular Surgery, Texas Heart Institute, Houston 77225.
Ann Thorac Surg. 1994 Jul;58(1):19-22; discussion 22-3. doi: 10.1016/0003-4975(94)91065-0.
With the advent of rapid autotransfusion, we began to repair aneurysms of the descending thoracic and thoracoabdominal aorta by using an "open" technique, in which a single cross-clamp is placed proximal to the aneurysm to exsanguinate the lower body. To determine whether open distal anastomosis effectively protects against spinal cord injury, we studied 71 consecutive patients (50 men, 21 women) who underwent this procedure beginning in April 1989. The patients ranged in age from 31 to 83 years (mean, 63.3 years). Most patients were hypertensive (n = 61; 86%) and symptomatic (n = 54; 76%). Most had been diagnosed with medial degeneration (n = 45; 63.4%) or aortic dissection (n = 16; 22.5%). Five patients (7.0%) were admitted with aortic rupture. We replaced the entire descending thoracic aorta in 31 (43.7%), the thoracoabdominal aorta in 21 (29.6%), and a segment of the descending thoracic aorta in 19 (26.7%). The average distal ischemic time was 22.4 minutes (range, 11 to 42 minutes). The amount of blood returned through the autotransfusion device averaged 2,099 mL. Eight patients (11.3%) died within 30 days (multiple organ failure, 3; hemorrhage, 2; coexisting ischemic heart disease, 3). Spinal cord dysfunction occurred in 6 patients (8.5%) (lower extremity paraparesis, 4; paraplegia, 2). Renal insufficiency requiring dialysis occurred in 4 patients (5.6%). We believe that the low incidence of spinal cord injury and renal insufficiency in this series may have resulted from the free draining of the intercostal and lumbar arteries during aortic occlusion, which decreases cerebrospinal fluid and central venous pressures.(ABSTRACT TRUNCATED AT 250 WORDS)
随着快速自体输血技术的出现,我们开始采用“开放”技术修复降主动脉和胸腹主动脉瘤,即在动脉瘤近端放置单一交叉夹闭装置以使下半身失血。为了确定开放远端吻合术是否能有效预防脊髓损伤,我们研究了1989年4月起接受该手术的71例连续患者(50例男性,21例女性)。患者年龄在31至83岁之间(平均63.3岁)。大多数患者患有高血压(n = 61;86%)且有症状(n = 54;76%)。大多数患者被诊断为中层退变(n = 45;63.4%)或主动脉夹层(n = 16;22.5%)。5例患者(7.0%)因主动脉破裂入院。我们替换了整个降主动脉31例(43.7%),胸腹主动脉21例(29.6%),降主动脉节段19例(26.7%)。平均远端缺血时间为22.4分钟(范围11至42分钟)。通过自体输血装置回输的平均血量为2099 mL。8例患者(11.3%)在30天内死亡(多器官功能衰竭3例;出血2例;并存缺血性心脏病3例)。6例患者(8.5%)出现脊髓功能障碍(下肢轻瘫4例;截瘫2例)。4例患者(5.6%)出现需要透析的肾功能不全。我们认为本系列中脊髓损伤和肾功能不全的低发生率可能是由于主动脉阻断期间肋间动脉和腰动脉的自由引流,这降低了脑脊液和中心静脉压。(摘要截选至250字)