Jo E R, Shin H J, Seo J H, Lee S H, Song G G, Pyo H J
Department of Internal Medicine, Guro Hospital, College of Medicine, Korea University, Seoul.
Korean J Intern Med. 1994 Jan;9(1):43-6. doi: 10.3904/kjim.1994.9.1.43.
Antiphospholipid antibody syndrome is a newly-defined clinical entity of arterial thrombosis, venous thrombotic events, recurrent spontaneous abortion and thrombocytopenia in the presence of antiphospholipid antibodies. We have experienced a 23-year-old male SLE patient with positive anticardiolipin antibody who presented with left hemiparesis and paresthesia. The clinical and laboratory findings were compatible with the criteria for SLE and he was found to have anticardiolipin antibody, thrombocytopenia, prolonged partial thromboplastin time and cerebral thrombosis. Initially, he was treated with high dose steroid and warfarin and now he is being followed up with warfarin and steroid.
抗磷脂抗体综合征是一种新定义的临床病症,表现为在存在抗磷脂抗体的情况下出现动脉血栓形成、静脉血栓事件、复发性自然流产和血小板减少。我们曾接诊一名23岁的男性系统性红斑狼疮(SLE)患者,其抗心磷脂抗体呈阳性,出现左半身轻瘫和感觉异常。临床和实验室检查结果符合SLE的诊断标准,且发现他存在抗心磷脂抗体、血小板减少、部分凝血活酶时间延长和脑血栓形成。最初,他接受了大剂量类固醇和华法林治疗,目前正在接受华法林和类固醇治疗并进行随访。