Papiha S S, Roberts D F
Clin Genet. 1975 Jan;7(1):77-82. doi: 10.1111/j.1399-0004.1975.tb00364.x.
Sera from multiple sclerosis patients show a deficit of intestinal alkaline phosphatase (serum type Pp2) by comparison with normal sera. This is not due to variation in ABO frequency, since the specimens from patients and normals are matched for ABO frequency, and it is not due to differences in secretor frequency, but represents a real dificit for Pp2 in patients with multiple sclerosis, particularly noticeable in group O individuals.
与正常血清相比，多发性硬化症患者的血清显示出肠碱性磷酸酶（血清型Pp2）缺乏。这并非由于ABO血型频率的差异，因为患者和正常人的样本在ABO血型频率上是匹配的，也不是由于分泌型频率的差异，而是代表多发性硬化症患者中Pp2的真正缺乏，在O型血个体中尤为明显。
