通过胰液的细胞学检查对胰腺良性和恶性黏液生成肿瘤进行鉴别诊断。
Cytologic examination of pancreatic juice for differential diagnosis of benign and malignant mucin-producing tumors of the pancreas.
作者信息
Uehara H, Nakaizumi A, Iishi H, Tatsuta M, Kitamra T, Okuda S, Ohigashi H, Ishikawa O, Takenaka A, Ishiguro S
机构信息
Department of Gastrointestinal Oncology, Center for Adult Diseases, Osaka, Japan.
出版信息
Cancer. 1994 Aug 1;74(3):826-33. doi: 10.1002/1097-0142(19940801)74:3<826::aid-cncr2820740307>3.0.co;2-7.
BACKGROUND
A new clinical type of pancreatic tumor, the mucin-producing tumor, has been recognized recently. However, it is not always easy to distinguish benign from malignant tumors preoperatively. In this study, three different methods of differentiating mucin-producing tumors of the pancreas were compared.
METHODS
Endoscopic ultrasonography, endoscopic retrograde pancreatography, and cytologic examination of pancreatic juice were performed in 14 patients who had mucin-producing pancreatic tumors (11 carcinomas and 3 adenomas). Pancreatic juice was collected endoscopically without papillotomy.
RESULTS
The sensitivity, specificity, and overall accuracy of endoscopic ultrasonography were 82%, 90%, and 79%, respectively; those of endoscopic retrograde pancreatography were 91%, 91%, and 86%; and those of cytologic examination were 91%, 100%, and 93%.
CONCLUSION
Cytologic examination of pancreatic juice was the best of these three methods for differentiating benign from malignant mucin-producing pancreatic tumors.
背景
一种新型的胰腺肿瘤，即产黏液肿瘤，最近已被确认。然而，术前区分良性和恶性肿瘤并非总是容易。在本研究中，比较了三种区分胰腺产黏液肿瘤的不同方法。
方法
对14例患有胰腺产黏液肿瘤（11例癌和3例腺瘤）的患者进行了内镜超声检查、内镜逆行胰胆管造影术以及胰液细胞学检查。在不进行乳头切开术的情况下通过内镜收集胰液。
结果
内镜超声检查的敏感性、特异性和总体准确率分别为82%、90%和79%；内镜逆行胰胆管造影术的分别为91%、91%和86%；细胞学检查的分别为91%、100%和93%。
结论
胰液细胞学检查是这三种区分胰腺产黏液肿瘤良恶性方法中最佳的方法。
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