Genco R J
Department of Oral Biology, State University of New York, Buffalo.
Compend Suppl. 1994(18):S678-83; quiz S714-7.
The Periodontal Disease Research Center at the State University of New York at Buffalo has studied two sets of subjects--those with a high prevalence of diabetes (the Pima Indians) and an urban population in Erie County, New York--to determine factors that put a patient at risk for periodontal disease. These and other studies have established that smoking and diabetes are important risk indicators for periodontal disease. Local etiologic factors associated with periodontal disease in adults include the presence of the putative periodontal pathogens Porphyromonas gingivalis and Bacteroides forsythus. Longitudinal studies and intervention studies are needed to fully establish the role of risk indicators. However, information already available from present studies suggests that modulation of risk factors, such as smoking and diabetes mellitus, as well as suppression of the pathogenic flora, will be effective in the management of periodontal disease.
纽约州立大学布法罗分校的牙周病研究中心对两组对象进行了研究，一组是糖尿病高发人群（皮马印第安人），另一组是纽约伊利县的城市人口，以确定使患者有患牙周病风险的因素。这些研究以及其他研究已证实，吸烟和糖尿病是牙周病的重要风险指标。与成人牙周病相关的局部病因包括公认的牙周病原体牙龈卟啉单胞菌和福赛斯坦纳菌的存在。需要进行纵向研究和干预研究来充分确定风险指标的作用。然而，目前研究已获得的信息表明，对吸烟和糖尿病等风险因素进行调节，以及抑制致病菌群，将对牙周病的治疗有效。
