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健康对照者和慢性牙周炎患者的血清铁蛋白水平及红细胞参数

Serum ferritin level and red blood cell parameters in healthy controls and chronic periodontitis patients.

作者信息

Latha S, Thirugnanamsambandan S, Arun R T, Masthan K M K, Malathi L, Rajesh E

机构信息

Department of Periodontics, K. G. F. Dental College and Hospital, Karnataka, India.

Department of Oral Pathology and Microbiology, K. G. F. Dental College and Hospital, Karnataka, India.

出版信息

J Pharm Bioallied Sci. 2015 Apr;7(Suppl 1):S184-9. doi: 10.4103/0975-7406.155896.

Abstract

Periodontitis, which is a chronic inflammatory disease causes reduction in the number of erythrocytes and hemoglobin. It is found to be caused by specific pathogenic subgingival plaque bacteria. Periodontitis is host mediated through release of pro inflammatory cytokines by local tissues and immune cells in response to bacterial flora and its products, especially lipopolysacharides. Periodontitis is found to have systemic effect and the cytokines produced inhibit proliferation and differentiation of erythrocytes leading to anaemia. This study evaluate level of hemoglobin erythrocytes, hematocrit and serum ferritin levels in healthy subjects and periodontitis patient.

摘要

牙周炎是一种慢性炎症性疾病,会导致红细胞数量和血红蛋白减少。它是由特定的龈下菌斑致病菌引起的。牙周炎是由局部组织和免疫细胞对细菌菌群及其产物(尤其是脂多糖)作出反应而释放促炎细胞因子介导的宿主反应。牙周炎具有全身影响,所产生的细胞因子会抑制红细胞的增殖和分化,导致贫血。本研究评估了健康受试者和牙周炎患者的血红蛋白、红细胞、血细胞比容和血清铁蛋白水平。

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