Mengel H
Novo Nordisk A/S, Måløv, Denmark.
Epilepsia. 1994;35 Suppl 5:S81-4. doi: 10.1111/j.1528-1157.1994.tb05976.x.
Tiagabine (TGB), a specific gamma-aminobutyric acid (GABA)-uptake inhibitor, is a potential new antiepileptic drug with a novel mechanism of action. In animal models of epilepsy as well as in a placebo-controlled trial in patients with complex partial seizures, TGB showed significant anticonvulsant effects. TGB was well tolerated by most patients.
替加宾（TGB）是一种特异性γ-氨基丁酸（GABA）摄取抑制剂，是一种具有新型作用机制的潜在新型抗癫痫药物。在癫痫动物模型以及一项针对复杂部分性发作患者的安慰剂对照试验中，TGB显示出显著的抗惊厥作用。大多数患者对TGB耐受性良好。
