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1
Bidirectional chromosome replication in Bacillus subtilis 168.枯草芽孢杆菌168中的双向染色体复制。
J Bacteriol. 1975 Mar;121(3):835-47. doi: 10.1128/jb.121.3.835-847.1975.
2
Revision of the linkage map of Bacillus subtilis 168: indications for circularity of the chromosome.枯草芽孢杆菌168连锁图谱的修订：染色体呈环状的证据
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3
Genetic mapping in Bacillus subtilis by 5-bromouracil sensitization to ultraviolet inactivation of transforming activities.通过5-溴尿嘧啶对枯草芽孢杆菌转化活性紫外线失活的敏感性进行遗传图谱分析。
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4
Asymmetric bidirectional replication of Bacillus subtilis chromosome.枯草芽孢杆菌染色体的不对称双向复制。
Nat New Biol. 1973 Aug 15;244(137):200-3. doi: 10.1038/newbio244200a0.
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Evidence for the Translocation of a Chromosome Sement in Bacillus subtilis Strains Carrying the trpE26 Mutation.携带trpE26突变的枯草芽孢杆菌菌株中染色体片段易位的证据。
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6
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Completed chromosomes in thymine-requiring Bacillus subtilis spores.胸腺嘧啶需求型枯草芽孢杆菌孢子中的完整染色体。
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J Bacteriol. 1980 Aug;143(2):1033-5. doi: 10.1128/jb.143.2.1033-1035.1980.
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Genetic transformation with cell wall-associated deoxyribonucleic acid in Bacillus subtilis.枯草芽孢杆菌中与细胞壁相关的脱氧核糖核酸的遗传转化
J Bacteriol. 1980 Dec;144(3):957-66. doi: 10.1128/jb.144.3.957-966.1980.
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The Bacillus subtilis chromosome.枯草芽孢杆菌染色体。
Microbiol Rev. 1980 Mar;44(1):57-82. doi: 10.1128/mr.44.1.57-82.1980.
4
Map locations of some mutations conferring resistance to arginine hydroxamate in Bacillus subtilis 168.枯草芽孢杆菌168中一些对精氨酸异羟肟酸盐具有抗性的突变的图谱定位。
Mol Gen Genet. 1980;178(3):691-701. doi: 10.1007/BF00337880.
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J Bacteriol. 1981 Jul;147(1):206-16. doi: 10.1128/jb.147.1.206-216.1981.
8
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Microbiol Rev. 1982 Sep;46(3):341-75. doi: 10.1128/mr.46.3.341-375.1982.
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DNA and protein sequence conservation at the replication terminus in Bacillus subtilis 168 and W23.枯草芽孢杆菌168和W23复制终点处的DNA和蛋白质序列保守性
J Bacteriol. 1989 Mar;171(3):1402-8. doi: 10.1128/jb.171.3.1402-1408.1989.
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Mapping the uroporphyrinogen decarboxylase, coproporphyrinogen oxidase and ferrochelatase loci in Bacillus subtilis.枯草芽孢杆菌中尿卟啉原脱羧酶、粪卟啉原氧化酶和亚铁螯合酶基因座的定位
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本文引用的文献

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REQUIREMENTS FOR TRANSFORMATION IN BACILLUS SUBTILIS.枯草芽孢杆菌转化的要求。
J Bacteriol. 1961 May;81(5):741-6. doi: 10.1128/jb.81.5.741-746.1961.
2
LINKAGE RELATIONSHIPS OF GENES CONTROLLING ISOLEUCINE, VALINE, AND LEUCINE BIOSYNTHESIS IN BACILLUS SUBTILIS.枯草芽孢杆菌中控制异亮氨酸、缬氨酸和亮氨酸生物合成的基因的连锁关系
J Bacteriol. 1965 Aug;90(2):357-69. doi: 10.1128/jb.90.2.357-369.1965.
3
SEQUENTIAL REPLICATION OF THE BACILLUS SUBTILIS CHROMOSOME. 3. REGULATION OF INITIATION.枯草芽孢杆菌染色体的连续复制。3. 起始调控。
Proc Natl Acad Sci U S A. 1964 Oct;52(4):973-80. doi: 10.1073/pnas.52.4.973.
4
Sequential replication of the Bacillus subtilis chromosome. II. Isotopic transfer experiments.枯草芽孢杆菌染色体的顺序复制。II. 同位素转移实验。
Proc Natl Acad Sci U S A. 1963 Jun;49(6):806-13. doi: 10.1073/pnas.49.6.806.
5
Sequential replication of Bacillus subtilis chromosome. I. Comparison of marker frequencies in exponential and stationary growth phases.枯草芽孢杆菌染色体的顺序复制。I. 指数生长期和稳定生长期标记频率的比较。
Proc Natl Acad Sci U S A. 1963 Apr;49(4):559-66. doi: 10.1073/pnas.49.4.559.
6
Characterization of two sucrase activities in Bacillus subtilis Marburg.枯草芽孢杆菌马伯格菌株中两种蔗糖酶活性的表征
Biochimie. 1971;53(10):1059-66. doi: 10.1016/s0300-9084(71)80193-1.
7
Genetic analysis of pleiotropic negative sporulation mutants in Bacillus subtilis.枯草芽孢杆菌多效性负向芽孢形成突变体的遗传分析。
J Bacteriol. 1971 Mar;105(3):896-901. doi: 10.1128/jb.105.3.896-901.1971.
8
Biochemical and genetic characterization of a temperature-sensitive, tryptophanyl-transfer ribonucleic acid synthetase mutant of Bacillus subtilis.枯草芽孢杆菌温度敏感型色氨酰转运核糖核酸合成酶突变体的生化及遗传学特性
J Bacteriol. 1971 Jan;105(1):6-19. doi: 10.1128/jb.105.1.6-19.1971.
9
Citric acid cycle: gene-enzyme relationships in Bacillus subtilis.柠檬酸循环：枯草芽孢杆菌中的基因-酶关系
J Bacteriol. 1970 Nov;104(2):826-33. doi: 10.1128/jb.104.2.826-833.1970.
10
Chromosomal location and properties of radiation sensitivity mutations in Bacillus subtilis.枯草芽孢杆菌中辐射敏感性突变的染色体定位及特性
J Bacteriol. 1970 Aug;103(2):295-301. doi: 10.1128/jb.103.2.295-301.1970.

枯草芽孢杆菌168中的双向染色体复制。

Bidirectional chromosome replication in Bacillus subtilis 168.

作者信息

Harford N

出版信息

J Bacteriol. 1975 Mar;121(3):835-47. doi: 10.1128/jb.121.3.835-847.1975.

DOI:10.1128/jb.121.3.835-847.1975
PMID:803964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC246010/
Abstract

Density transfer analysis of deoxyribonucleic acid from Bacillus subtilis 168 thy spores germinating in 5-bromouracil medium shows the order of replication of genetic markers to be: purA16, cysA14, sacA, ctrA, (narB, arol), dal, (hisA1, purB6), (tre-12, thr-5), (argA, aroG, argC4), (metC, leu-8, pheA), (ura-1, aroD), lys-1, (trpC, metB, ilvA, citB, citK, gltA). The precise order of transfer of markers within parentheses could not be determined in these experiments. Taken together with new PBS1 transduction data presented here and in the accompanying paper of J. Lepesant-Kejzlarová, J.-A. Lepesant, J. Walle, A. Billaut, and R. Dedonder (1975), the results can be resolved in terms of a symmetric, fully bidirectional mode of chromosome replication with a replication origin close to the purA16 marker and a terminus in the region of the gltA, citK loci, diametrically opposed to the origin. A new genetic map of the B. subtilis 168 chromosome is presented.

摘要

对在5-溴尿嘧啶培养基中萌发的枯草芽孢杆菌168 thy孢子的脱氧核糖核酸进行密度转移分析，结果表明遗传标记的复制顺序为：purA16、cysA14、sacA、ctrA、(narB, arol)、dal、(hisA1, purB6)、(tre-12, thr-5)、(argA, aroG, argC4)、(metC, leu-8, pheA)、(ura-1, aroD)、lys-1、(trpC, metB, ilvA, citB, citK, gltA)。在这些实验中无法确定括号内标记转移的精确顺序。结合本文以及J. Lepesant-Kejzlarová、J.-A. Lepesant、J. Walle、A. Billaut和R. Dedonder（1975年）的相关论文中给出的新的PBS1转导数据，这些结果可以用染色体复制的对称、完全双向模式来解释，复制起点靠近purA16标记，终点位于gltA、citK基因座区域，与起点相对。本文给出了枯草芽孢杆菌168染色体的新遗传图谱。