恶性疟原虫类质体样DNA上的九个重复tRNA基因。

Nine duplicated tRNA genes on the plastid-like DNA of the malaria parasite Plasmodium falciparum.

作者信息

Gardner M J, Preiser P, Rangachari K, Moore D, Feagin J E, Williamson D H, Wilson R J

机构信息

National Institute for Medical Research, Mill Hill, London, UK.

出版信息

Gene. 1994 Jul 8;144(2):307-8. doi: 10.1016/0378-1119(94)90395-6.

DOI:10.1016/0378-1119(94)90395-6

PMID:8039718

Abstract

A major feature of the plastid-like circular DNA of Plasmodium falciparum is an inverted repeat comprising duplicated genes for rRNA (rrn) and tRNA (trn). We have identified nine putative trn genes in each arm of the repeat on the basis of their potential clover-leaf structures and conserved residues. Northern blots indicate that these trn genes are expressed.

摘要

恶性疟原虫类质体环状DNA的一个主要特征是一个反向重复序列，它包含rRNA（rrn）和tRNA（trn）的重复基因。基于其潜在的三叶草叶形结构和保守残基，我们在重复序列的每条臂中鉴定出了9个假定的trn基因。Northern印迹表明这些trn基因是有表达的。