Maxson S, Lewno M J, Schutze G E
Division of Infectious Diseases, Arkansas Children's Hospital, Little Rock 72202.
J Pediatr. 1994 Aug;125(2):235-8. doi: 10.1016/s0022-3476(94)70201-2.
A retrospective chart review was performed to evaluate the effect that positive results of cerebrospinal fluid bacterial antigen tests had on the care of patients with presumed bacterial meningitis. Of 901 tests ordered, costing $26,000 per year, 29 showed positive results--and only four of these affected patient care. By using cerebrospinal fluid bacterial antigen testing only when another test does not identify an organism, or in an attempt to determine central nervous system infection late in therapy for presumed sepsis, one can greatly reduce costs with no detrimental effect on patients.
进行了一项回顾性病历审查，以评估脑脊液细菌抗原检测阳性结果对疑似细菌性脑膜炎患者治疗的影响。在每年花费26,000美元进行的901次检测中，有29次结果呈阳性，其中只有4次对患者治疗产生了影响。仅在其他检测无法鉴定病原体时，或在试图确定疑似脓毒症治疗后期的中枢神经系统感染时使用脑脊液细菌抗原检测，就可以在不影响患者的情况下大幅降低成本。
