Taeusch H W, Supnet M
Department of Pediatrics, Charles R. Drew University of Medicine and Science, Los Angeles, California.
J Natl Med Assoc. 1994 Apr;86(4):297-302.
This article analyzes birthweight, gestational age, and inhospital survival for 233 extremely premature infants born at an inner-city hospital over the past 5 years. Results for gestation-specific birthweights and survival did not differ between inner-city Hispanic and African-American infants born at 24 to 28 weeks of gestation. For infants with gestation of 23 to 28 weeks, weight at birth increased by approximately 100 g/week gestation. Survival rates increased from 15% at 23 weeks to 75% by 28 weeks gestation. Survival in this sample was strongly affected by respiratory distress syndrome, air leak, and birthweight. Prenatal steroids administered to the mother had a significant effect on improving survival using univariate analysis and was at the limits of statistical significance using logistic regression. Other maternal, obstetric, and neonatal factors had little or no effects on survival in this group of very immature infants.
本文分析了过去5年在一家市中心医院出生的233名极早产儿的出生体重、孕周和住院存活率。孕周特定的出生体重和存活率在市中心西班牙裔和非裔美国裔孕24至28周出生的婴儿之间没有差异。对于孕23至28周的婴儿，出生体重每周约增加100克。存活率从孕23周时的15%增加到孕28周时的75%。该样本中的存活率受到呼吸窘迫综合征、气漏和出生体重的强烈影响。单因素分析显示，给母亲使用产前类固醇对提高存活率有显著影响，逻辑回归分析显示其处于统计学意义的临界值。其他母亲、产科和新生儿因素对这组极不成熟婴儿的存活率几乎没有影响。
