Kumar H, Naqvi S A, Ahmed A, Hamid S
Department of Nephrourology, Aga Khan University Hospital, Karachi.
J Pak Med Assoc. 1994 Feb;44(2):28-30.
Anti HCV was checked using Enzyme Immuno assay (EIA) (C100-3-Abbott) in 68 patients with chronic renal failure (CRF) who were on maintenance haemodialysis and 48 patients on conservative management. Mean age of the patients was 50 years. The duration of illness ranged from 3 months to 18 years (mean 3 years). All patients were Hepatitis B surface antigen (HBsAg) negative. In haemodialyzed group 31 (46%) and in conservative group only 3 (6%) were Anti HCV positive. High Frequency of Anti HCV positivity in haemodialyzed group was related to period on dialysis (1 year) and number of blood transfusions (>4 units). Patients in whom dialyzer was re-used showed 60% positivity as compared to only 17% in those with single use. Anti HCV positivity predominated in females as compared to males, 42.6% vs 20.3%. Nine out of 10 patients with a history of jaundice and six out of 8 patients with raised transaminase levels were Anti HCV positive. Fifteen of 37 Anti HBc (IgG) positive cases were Anti HCV +ve.
采用酶免疫测定法（EIA）（C100-3-雅培）对68例维持性血液透析的慢性肾衰竭（CRF）患者和48例保守治疗的患者进行抗丙型肝炎病毒（Anti HCV）检测。患者的平均年龄为50岁。病程为3个月至18年（平均3年）。所有患者乙型肝炎表面抗原（HBsAg）均为阴性。血液透析组中31例（46%）抗丙型肝炎病毒阳性，而保守治疗组中仅3例（6%）阳性。血液透析组抗丙型肝炎病毒阳性率高与透析时间（1年）和输血次数（>4单位）有关。重复使用透析器的患者阳性率为60%，而一次性使用透析器的患者阳性率仅为17%。女性抗丙型肝炎病毒阳性率高于男性，分别为42.6%和20.3%。10例有黄疸病史的患者中有9例抗丙型肝炎病毒阳性，8例转氨酶水平升高的患者中有6例阳性。37例抗乙型肝炎核心抗体（IgG）阳性病例中有15例抗丙型肝炎病毒阳性。
