Klencki M, Słowińska-Klencka D, Sporny S, Lewiński A
Department of Thyrology, University School of Medicine, Lódź, Poland.
Acta Cytol. 1994 Jul-Aug;38(4):524-6.
It is believed that the size of thyrocyte nuclei correlates with the age of the patient in both normal thyroid tissue and nodular goiter. Therefore, we examined karyometric parameters in aspirates obtained from 38 patients ranging from 18 to 79 years (48.8 +/- 15.2, mean +/- SD). Routine cytologic evaluation revealed nodular goiters in all the patients. Subsequently, the same smears were analyzed with a computer system for karyometric measurements. The mean volume, intersection area and perimeter of nuclei of thyrocytes from nodular goiters correlated positively with age. The results suggest that the age of the patient should be considered when interpreting thyrocyte nuclear size during cytologic examination.
据信，在正常甲状腺组织和结节性甲状腺肿中，甲状腺细胞核的大小与患者年龄相关。因此，我们检查了38例年龄在18至79岁（平均48.8±15.2，均值±标准差）患者的穿刺物中的核测量参数。常规细胞学评估显示所有患者均为结节性甲状腺肿。随后，使用计算机系统对相同涂片进行核测量分析。结节性甲状腺肿中甲状腺细胞核的平均体积、交叉面积和周长与年龄呈正相关。结果表明，在细胞学检查中解释甲状腺细胞核大小时应考虑患者年龄。
