Rohen J W, Schachtschabel O O, Matthiessen P F
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975;193(2):95-107. doi: 10.1007/BF00419354.
Small pieces of the chamber angle region of a vervet eye containing only a lamella of the corneosclera and the trabecular meshwork were cultured in vitro and studied by light and electron microscopy at various intervals. The explanted trabecular meshwork underwent a rapid dedifferentiation. The activation of the trabecular cells is demonstrated by an increasing amount of encoplasmic reticulum, ribosomes and mitochondria. They are capable of phagocytosis for detritus and pigment granules. In the 45-day-tissue culture the trabecular cells revealed many lipid inclusions. In the culture the trabecular lamellae gradually dissolve, whereas the basement membranes and the elastic fibers remain unchanged for the longest. An increase or change in the clusters of lattice or curly collagen is not seen.
取成年绿猴眼房角区的小块组织，仅包含一层角膜巩膜和小梁网，进行体外培养，并在不同时间间隔用光镜和电镜进行研究。移植的小梁网迅速去分化。小梁细胞的激活表现为内质网、核糖体和线粒体数量增加。它们能够吞噬碎屑和色素颗粒。在45天的组织培养中，小梁细胞出现许多脂质包涵体。在培养过程中，小梁薄片逐渐溶解，而基底膜和弹性纤维保持最长时间不变。未见格子状或卷曲状胶原簇的增加或改变。
