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[多次输血患者丙型肝炎病毒血清流行率研究]

[A seroprevalence study of the hepatitis C virus among multiply transfused patients].

作者信息

Antipa C, Popescu A, Teleguţă M, Ruţă S, Cernescu C, Târdei G, Copelovici Y, Stoian M, Tivgă N, Hoinărescu M

机构信息

Institut de Virologie Stefan S. Nicolau, Bucarest, Roumanie.

出版信息

Rev Roum Virol. 1993 Jan-Jun;44(1-2):9-15.

PMID:8043483
Abstract

A study was conducted on 61 polytransfused patients, 24 patients submitted to long lasting parenteral treatments, 116 blood donors and 132 controls. Immuno-enzymatic tests were used for detection of antibodies against hepatitis C virus (HCV). They were found in 56 (91.8%) out of the 61 polytransfused patients, in 5 (4.3%) of the donors, in 5 (20.8%) of the patients with multiple treatments and in 5 (3.7%) controls. The VHB markers were detected at variable rates in all investigated groups. The high rate of seropositivity indicates that hepatitis C is becoming an important public health problem in Romania.

摘要

对61例多次输血患者、24例接受长期非肠道治疗的患者、116名献血者和132名对照者进行了一项研究。采用免疫酶试验检测抗丙型肝炎病毒(HCV)抗体。在61例多次输血患者中有56例(91.8%)检测到抗体,在献血者中有5例(4.3%),在接受多种治疗的患者中有5例(20.8%),在对照者中有5例(3.7%)检测到抗体。在所有研究组中均以不同比率检测到乙肝病毒标志物。高血清阳性率表明丙型肝炎正在成为罗马尼亚一个重要的公共卫生问题。

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