Houlihan D J, Flaum M, Arnold S E, Keshavan M, Alliger R
Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213.
Schizophr Res. 1994 May;12(2):179-82. doi: 10.1016/0920-9964(94)90075-2.
Forty-seven schizophrenic patients and 36 normal controls, matched for smoking history, were administered the University of Pennsylvania Smell Identification Test (UPSIT) and the Picture Identification Test (PIT). Amongst subjects successfully completing the PIT, non-smoking schizophrenic patients had significantly lower UPSIT scores than non-smoking controls. Smoking history and diagnosis did not interact to produce any pronounced effect. No significant gender difference was found. These results suggest schizophrenics display decreased olfactory identification even if likely confounders are adequately controlled.
47名精神分裂症患者和36名与吸烟史相匹配的正常对照者接受了宾夕法尼亚大学嗅觉识别测试(UPSIT)和图片识别测试(PIT)。在成功完成PIT的受试者中,不吸烟的精神分裂症患者的UPSIT得分显著低于不吸烟的对照组。吸烟史和诊断并未相互作用产生任何显著影响。未发现显著的性别差异。这些结果表明,即使可能的混杂因素得到充分控制,精神分裂症患者的嗅觉识别能力仍会下降。