Meerson F Z, Miniaĭlenko T D, Pozharov V P
Biull Eksp Biol Med. 1993 Feb;115(2):132-5.
Adaptation to intermittent short-term immobilization stress exposure increases the resistance of rats to hypoxic hypoxia. This was evidenced by the fact that in acute experiments in respiration with gas-mixture containing 6% of oxygen, the mortality of control rats was 65% compared with 10% of that of adapted rats. It has been estimated that this protective cross-effect of adaptation to stress is due to more stable and efficient mobilization of external respiration in adapted animals, and to a greater extent, to the fact that adapted rats tissues have gained a capacity of extracting more oxygen from hypoxemic blood compared to control animals. The role of previously stated phenomenon of adaptive stabilization of structures in superresistance to hypoxic hypoxia is discussed.
适应间歇性短期固定应激暴露可增强大鼠对低氧性缺氧的抵抗力。这一点在急性实验中得到了证实，即在使用含6%氧气的混合气体进行呼吸实验时，对照大鼠的死亡率为65%，而适应应激的大鼠死亡率仅为10%。据估计，这种对应激适应的保护性交叉效应是由于适应应激的动物在外部呼吸方面能更稳定、高效地动员，并且在更大程度上是因为与对照动物相比，适应应激的大鼠组织从低氧血症血液中提取更多氧气的能力增强。文中还讨论了先前所述的结构适应性稳定现象在对低氧性缺氧的超强抵抗力中的作用。
