Osipov A V, Kukushkin M L
Biull Eksp Biol Med. 1993 May;115(5):471-3.
Effect of immobilization and painful stress on the development of deafferentation pain syndrome, appeared after sciatic nerve section, has been studied in Wistar rats. It has been determined that both immobilization and painful stress favour the appearance of pain syndrome in rats without clinical signs of pain syndrome up to the moment of stress influence. There has been made a conclusion that both immobilization and painful stress favour the appearance of pathologic algic system, which is the basis of pain syndrome. The fact that stress can cause analgesia in normal animals in contrast to those with potential pain syndrome is explained to different mechanisms of physiological and pathological pain.
