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儿童肝脓肿的保守初始治疗

Conservative initial treatment for liver abscesses in children.

作者信息

Moore S W, Millar A J, Cywes S

机构信息

Department of Paediatric Surgery, Institute of Child Health, Cape Town, South Africa.

出版信息

Br J Surg. 1994 Jun;81(6):872-4. doi: 10.1002/bjs.1800810626.

Abstract

A total of 124 children aged less than 14 years with a liver abscess were seen in a 16-year period (1974-1990) and treated by non-operative initial management. Of the abscesses 98 occurred in the right liver and 26 in the left. The abscesses were solitary in 93 patients. Overall, 77 of the solitary and 21 of the multiple abscesses were confined to the right liver. In 78 of the right-sided and 20 of the left-sided abscesses the infection was primarily pyogenic in nature with Staphylococcus aureus being the usual organism cultured. The remainder were of amoebic origin. Clinical features were similar in patients with amoebic and pyogenic abscesses. Clinical and ultrasonographic follow-up demonstrated successful non-operative management and healing in 37 per cent of all patients submitted to an initial protocol of medical supportive care and antibiotic therapy. Of the multiple abscesses 60 per cent responded to non-operative management. Fourteen of the 16 solitary left-sided liver abscesses required drainage and three left-sided abscesses ruptured before drainage. Patients with a solitary left-sided abscess warrant early operative intervention.

摘要

在16年期间(1974 - 1990年),共收治了124名14岁以下患有肝脓肿的儿童,并采用非手术初始治疗。其中,98个脓肿位于右肝,26个位于左肝。93例患者的脓肿为单发。总体而言,单发脓肿中有77个、多发脓肿中有21个局限于右肝。在右侧脓肿78例和左侧脓肿20例中,感染主要为化脓性,常见培养出的病原体为金黄色葡萄球菌。其余为阿米巴源性。阿米巴脓肿和化脓性脓肿患者的临床特征相似。临床和超声随访显示,在所有接受初始药物支持治疗和抗生素治疗方案的患者中,37%通过非手术治疗成功治愈。多发脓肿中60%对非手术治疗有反应。16例单发左侧肝脓肿中有14例需要引流,3例左侧脓肿在引流前破裂。单发左侧脓肿患者需要早期手术干预。

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