卡介苗局部治疗牛外阴乳头瘤和癌
Local bacillus Calmette-Guérin therapy for bovine vulval papilloma and carcinoma.
作者信息
Hill F W, Rutten V P, Hoyer M H, Klein W R, Koten J W, Steerenberg P A, Ruitenberg E J, Den Otter W
机构信息
Faculty of Veterinary Science, University of Zimbabwe, Harare.
出版信息
Cancer Immunol Immunother. 1994 Jul;39(1):49-52. doi: 10.1007/BF01517180.
Abstract
Thirty cows from a pedigree Friesian dairy herd with bovine vulva papilloma and carcinoma were treated by intralesional injections of live bacillus Calmette-Guérin (BCG). This treatment induced total regression of all of six carcinomas. Whilst, after treatment, limited regression was also observed in advanced papillomas, BCG has little or no effect on the early stages of papillomas. This is the first study of BCG therapy in this type of cancer.
摘要
对30头患有牛外阴乳头瘤和癌的纯种弗里斯兰奶牛，通过病灶内注射活卡介苗（BCG）进行治疗。该治疗使所有6例癌完全消退。虽然治疗后，晚期乳头瘤也出现了有限的消退，但卡介苗对乳头瘤的早期阶段几乎没有影响。这是卡介苗疗法在这类癌症中的首次研究。
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本文引用的文献
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Antitumor effect of locally injected low doses of recombinant human interleukin-2 in bovine vulval papilloma and carcinoma.
Vet Immunol Immunopathol. 1994 May;41(1-2):19-29. doi: 10.1016/0165-2427(94)90054-x.
2
Immunotherapy by intralesional injection of BCG cell walls or live BCG in bovine ocular squamous cell carcinoma: a preliminary report.
J Natl Cancer Inst. 1982 Nov;69(5):1095-103.
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Efficacy of intratumorally administered mycobacterial cell walls in the treatment of cattle with ocular carcinoma.瘤内注射分枝杆菌细胞壁治疗牛眼癌的疗效
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Regression of bovine vulval squamous cell carcinoma after immunotherapy.免疫治疗后牛外阴鳞状细胞癌的消退
Aust Vet J. 1989 Jun;66(6):186-7. doi: 10.1111/j.1751-0813.1989.tb09800.x.
7
Local interleukin-2 therapy in bovine ocular squamous cell carcinoma. A pilot study.牛眼鳞状细胞癌的局部白细胞介素-2治疗。一项试点研究。
Cancer Immunol Immunother. 1989;30(3):165-9. doi: 10.1007/BF01669425.
8
Immunotherapy of bovine ocular squamous cell carcinoma by repeated intralesional injections of live bacillus Calmette-Guérin (BCG) or BCG cell walls.通过瘤内反复注射活卡介苗（BCG）或BCG细胞壁对牛眼鳞状细胞癌进行免疫治疗。
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9
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J Natl Cancer Inst. 1977 Jun;58(6):1807-14. doi: 10.1093/jnci/58.6.1807.
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