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用一种分枝杆菌疫苗治疗牛眼癌的消退情况

Regression of bovine ocular carcinoma by treatment with a mycobacterial vaccine.

作者信息

Kleinschuster S J, Rapp H J, Lueker D C, Kainer R A

出版信息

J Natl Cancer Inst. 1977 Jun;58(6):1807-14. doi: 10.1093/jnci/58.6.1807.

DOI:10.1093/jnci/58.6.1807
PMID:864757
Abstract

Hereford cows with naturally occurring ocular squamous cell carcinoma were treated by injection of BCG cell-wall vaccine into the tumor. Regression or arrest of disease was observed in 71% of treated animals. The disease progressed in all untreated animals and animals treated with improperly compounded vaccine. At autopsy, most animals with progressive disease had lymph node metastases.

摘要

对患有自然发生的眼鳞状细胞癌的赫里福德奶牛,通过向肿瘤内注射卡介苗细胞壁疫苗进行治疗。在71%的接受治疗的动物中观察到疾病消退或停滞。在所有未治疗的动物以及用配制不当的疫苗治疗的动物中,疾病均有进展。尸检时,大多数患有进展性疾病的动物有淋巴结转移。

相似文献

1
Regression of bovine ocular carcinoma by treatment with a mycobacterial vaccine.用一种分枝杆菌疫苗治疗牛眼癌的消退情况
J Natl Cancer Inst. 1977 Jun;58(6):1807-14. doi: 10.1093/jnci/58.6.1807.
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Efficacy of intratumorally administered mycobacterial cell walls in the treatment of cattle with ocular carcinoma.瘤内注射分枝杆菌细胞壁治疗牛眼癌的疗效
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Immunotherapy by intralesional injection of BCG cell walls or live BCG in bovine ocular squamous cell carcinoma: a preliminary report.
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Immunotherapy of experimental cancer as a guide to the treatment of human cancer.实验性癌症的免疫疗法作为人类癌症治疗的指南。
Ann N Y Acad Sci. 1976;276:550-6. doi: 10.1111/j.1749-6632.1976.tb41681.x.
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Intratumoral bcg cell-wall preparation therapy and surgery in bovine ocular carcinoma.牛眼癌的瘤内卡介苗细胞壁制剂治疗与手术
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Immunotherapy of bovine ocular squamous cell carcinoma by repeated intralesional injections of live bacillus Calmette-Guérin (BCG) or BCG cell walls.通过瘤内反复注射活卡介苗(BCG)或BCG细胞壁对牛眼鳞状细胞癌进行免疫治疗。
Cancer Immunol Immunother. 1991;34(3):186-90. doi: 10.1007/BF01742311.
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[Immunotherapy of squamous cell carcinoma of the bovine eye and of equine sarcoid].
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Immunotherapy of bovine ocular squamous cell carcinomas.牛眼鳞状细胞癌的免疫疗法。
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Clinico-pathological aspects of immunotherapy by intralesional injection of BCG cell walls or live BCG in bovine ocular squamous cell carcinoma.通过病灶内注射卡介苗细胞壁或活卡介苗对牛眼鳞状细胞癌进行免疫治疗的临床病理学方面
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引用本文的文献

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Cancer Immunol Immunother. 1994 Jul;39(1):49-52. doi: 10.1007/BF01517180.
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Anchorage-dependent culture of line 10 guinea-pig hepatoma cells.10号线豚鼠肝癌细胞的贴壁依赖性培养
Experientia. 1980 Oct 15;36(10):1239-40. doi: 10.1007/BF01976152.
3
Influence of type of oil and surfactant concentration on the efficacy of emulsified Mycobacterium bovis BCG cell walls to induce tumor regression in guinea pigs.
油的类型和表面活性剂浓度对乳化的牛分枝杆菌卡介苗细胞壁诱导豚鼠肿瘤消退功效的影响。
Infect Immun. 1980 Jun;28(3):881-6. doi: 10.1128/iai.28.3.881-886.1980.
4
The immunopathological effects of intracolonic injection of Mycobacterium bovis BCG cell wall emulsions in guinea pigs.豚鼠结肠内注射牛分枝杆菌卡介苗细胞壁乳剂的免疫病理效应
Cancer Immunol Immunother. 1982;13(3):198-204. doi: 10.1007/BF00205389.
5
Experimental screening of BCG preparations produced for cancer immunotherapy: safety and immunostimulating and antitumor activity of four consecutively produced batches.用于癌症免疫治疗的卡介苗制剂的实验筛选:连续生产的四批产品的安全性、免疫刺激和抗肿瘤活性
Cancer Immunol Immunother. 1984;17(1):18-27. doi: 10.1007/BF00205492.
6
Successful tumour immunotherapy: possible role of antibodies to anti-inflammatory factors produced by neoplasms.成功的肿瘤免疫疗法:针对肿瘤产生的抗炎因子的抗体的可能作用。
Clin Exp Immunol. 1985 Jul;61(1):109-17.
7
Clinico-pathological aspects of immunotherapy by intralesional injection of BCG cell walls or live BCG in bovine ocular squamous cell carcinoma.通过病灶内注射卡介苗细胞壁或活卡介苗对牛眼鳞状细胞癌进行免疫治疗的临床病理学方面
Cancer Immunol Immunother. 1985;20(3):223-30. doi: 10.1007/BF00205581.
8
Immunotherapy of bovine ocular squamous cell carcinoma by repeated intralesional injections of live bacillus Calmette-Guérin (BCG) or BCG cell walls.通过瘤内反复注射活卡介苗(BCG)或BCG细胞壁对牛眼鳞状细胞癌进行免疫治疗。
Cancer Immunol Immunother. 1991;34(3):186-90. doi: 10.1007/BF01742311.
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Infect Immun. 1979 Sep;25(3):1087-9. doi: 10.1128/iai.25.3.1087-1089.1979.