每月一次复方注射用避孕药的代谢效应。世界卫生组织长效全身用生育调节制剂特别工作组，瑞士日内瓦。
Metabolic effects of once-a-month combined injectable contraceptives. The World Health Organization Task Force on Long-Acting Systemic Agents for Fertility Regulation, Geneva, Switzerland.
作者信息
Giwa-Osagie O F
机构信息
Department of Obstetrics and Gynaecology, College of Medicine, University of Lagos, Nigeria.
出版信息
Contraception. 1994 May;49(5):421-33. doi: 10.1016/0010-7824(94)90001-9.
The results of metabolic studies on once-a-month combined injectable contraceptives are summarized, focusing on four preparations: dihydroxyprogesterone acetophenide 150 mg/estradiol enanthate 10 mg; depot-medroxyprogesterone acetate 25 mg/estradiol cypionate 5 mg; norethisterone enanthate 50 mg/estradiol valerate 5 mg; and 17 beta-hydroxyprogesterone caproate 250 mg/estradiol valerate 5 mg. Their effects on carbohydrate metabolism, lipid metabolism, hemostasis, serum prolactin, cortisol, binding globulins and liver functions are reviewed. Areas requiring further research are identified.
总结了每月注射一次的复方避孕针剂的代谢研究结果，重点关注四种制剂：醋苯双羟孕酮150毫克/庚酸雌二醇10毫克；醋酸甲羟孕酮长效注射剂25毫克/环戊丙酸雌二醇5毫克；庚酸炔诺酮50毫克/戊酸雌二醇5毫克；以及己酸17β-羟孕酮250毫克/戊酸雌二醇5毫克。综述了它们对碳水化合物代谢、脂质代谢、止血、血清催乳素、皮质醇、结合球蛋白和肝功能的影响。确定了需要进一步研究的领域。
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