Hassan E O, el-Nahal N, el-Hussein M
Ob/Gyn Dept., Mansoura University, Cairo, Egypt.
Contraception. 1994 May;49(5):469-88. doi: 10.1016/0010-7824(94)90005-1.
A study of the acceptability of two once-a-month injectable contraceptives, Cyclofem and Mesigyna, in Egypt included 1091 women participating in the clinical trial of the two methods carried out during the period from November 1989 to July 1992. The acceptability of the two contraceptives proved to be high when measured by the rate of continuation at 12 months of injectable use, by method satisfaction, service satisfaction, rec recommending use to others, intent of future use, as well as willingness to pay for them when the injectables are marketed. The most important determinants of use discontinuation were young age, large family size, first time contraceptive use, previous experience with menstrual problems, dissatisfaction with clinic services, lack of counseling, lack of social support, as well as the husband's negative attitude towards contraceptive use. Side effects were more frequently reported by discontinuers; however, continuers appeared to be more tolerant of the same side effects. This study provided in-depth information about the social aspects affecting the acceptability of monthly injectable contraceptives in the different Egyptian localities, in addition to its being useful in monitoring activities in the clinical setting during these trials.
一项关于两种每月注射一次的避孕药（Cyclofem和Mesigyna）在埃及可接受性的研究，纳入了1091名参与1989年11月至1992年7月期间这两种方法临床试验的女性。通过注射使用12个月时的持续率、方法满意度、服务满意度、向他人推荐使用的情况、未来使用意图以及注射剂上市时为其付费的意愿来衡量，这两种避孕药的可接受性很高。使用中断的最重要决定因素包括年龄小、家庭规模大、首次使用避孕药、既往有月经问题经历、对诊所服务不满、缺乏咨询、缺乏社会支持以及丈夫对避孕使用的消极态度。中断使用者更频繁地报告副作用；然而，持续使用者似乎对相同的副作用更耐受。这项研究除了有助于监测这些试验期间临床环境中的活动外，还提供了有关影响埃及不同地区每月注射避孕药可接受性的社会方面的深入信息。
