Morrison P J, Nevin N C
Department of Medical Genetics, Queen's University of Belfast, Belfast City Hospital.
Ir J Med Sci. 1994 May;163(5):236-7. doi: 10.1007/BF02943258.
Serum iron, total iron binding capacity and ferritin was estimated in 42 patients with early Huntington disease (HD) and in 148 matched controls. Ferritin levels were significantly low in affected male subjects as compared to controls. Iron levels and total iron binding capacity were normal in HD patients. The importance of this finding, that occurs early in the pathogenesis of HD, is unknown.
对42例早期亨廷顿病(HD)患者和148例匹配的对照者进行了血清铁、总铁结合力和铁蛋白的测定。与对照组相比,患病男性受试者的铁蛋白水平显著降低。HD患者的铁水平和总铁结合力正常。这一在HD发病机制早期出现的发现的重要性尚不清楚。