Verhulst G, Vandersteen N, van Steirteghem A C, Devroey P
Centre for Reproductive Medicine, University Hospital, Brussels Free University, Belgium.
Hum Reprod. 1994 Apr;9(4):624-8. doi: 10.1093/oxfordjournals.humrep.a138560.
The question whether salpingectomy has a negative influence on ovarian function and the outcome of pregnancy in an in-vitro fertilization (IVF) and embryo transfer treatment programme is not yet answered. We performed a retrospective case-control study to investigate the possible negative effect of salpingectomy on ovarian response to human menopausal gonadotrophins (HMG) during IVF and embryo transfer. The study group was composed of 26 patients with bilateral salpingectomy. In 67 cycles we analysed different parameters of ovulation such as the number of days of ovarian stimulation, numbers of ampoules of HMG, pre-ovulatory oestradiol concentrations and the numbers of oocytes retrieved. These parameters were compared to a control group of 134 cycles in 134 women with healthy Fallopian tubes. No differences were found. Implantation ratio, pregnancy rate and outcome were the same in both groups. We conclude that bilateral salpingectomy had no detrimental effect on ovarian performance during IVF and embryo transfer treatment nor on the outcome.
输卵管切除术对体外受精（IVF）及胚胎移植治疗方案中的卵巢功能和妊娠结局是否有负面影响这一问题尚未得到解答。我们进行了一项回顾性病例对照研究，以调查输卵管切除术对IVF及胚胎移植期间卵巢对人绝经期促性腺激素（HMG）反应的可能负面影响。研究组由26例双侧输卵管切除患者组成。在67个周期中，我们分析了不同的排卵参数，如卵巢刺激天数、HMG安瓿数、排卵前雌二醇浓度及获取的卵母细胞数。这些参数与134例输卵管健康女性的134个周期的对照组进行了比较。未发现差异。两组的着床率、妊娠率及结局相同。我们得出结论，双侧输卵管切除术对IVF及胚胎移植治疗期间的卵巢功能及结局均无不利影响。
